Cyprtolocker Variances such as the recent "WannaCry" have been around for years. The main reason this hit the news headlines is of big outbreaks across the NHS and other global organisations.

Per below we've put together a list of things you can do to mitigate this for this strain and other strains :

http://www.response-it.co.uk/news/2016/10/27/ransomware-the-small-business-guide?rq=Cryptolocker

Install the MS17-010 update that patches the vulnerability in Windows

Done with finding out the version? Here are the links to the updates for all of the Windows versions for which it has been released. Note that if you aren’t sure if you use 32-bit or 64-bit version of Windows, you can simply download both patches — one of them will work for you; trying to run the wrong one will bring up an error box but will do no harm.

You can also be extreme and disable SMB 1 totally from your network however careful with this as things such as VCentre use this for domain authetnication!

Microsoft have put together a full list here thats uses SMB1

https://blogs.technet.microsoft.com/filecab/2017/06/01/smb1-product-clearinghouse/